Cumulative publications (from 2005)

See publications pre-2005

2009

Last updated 8 September, 2009

Braun, M., Drummond, D.R., Cross, R.A. and McAinsh, A.D.  (2009) The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism. Nature Cell Biol., 11: 724-730.

Ors, A., Grimaldi, M., Kimata, Y., Wilkinson, C.R.M., Jones, N. and Yamano, H.  (2009) The transcription factor Atf1 binds and activates the APC/C ubiquitin ligase in fission yeast. J. Biol. Chem., 284: 23989-23994.

Yamano, H., Trickey, M. Grimaldi, M. and Kimata, Y. (2009) In vitro assays for the anaphase-promoting complex/cyclosome (APC/C) in Xenopus egg extracts. Methods Mol. Biol., 545: 287-300.

McClelland, S.E. and McAinsh, A.D.  (2009)  Hydrodynamic analysis of human kinetochore complexes during mitosis.  Methods Mol. Biol. 545: 81-98.

Deng, W., Malecová, B., Oelgeschläger, T. and Roberts, S.G.E. (2009) TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation. Mol. Cell. Biol., 29: 1389-1400.

Toso, A., Winter, J.R., Garrod, A.J., Amaro, A.C., Meraldi, P. and McAinsh, A.D. (2009) Kinetchore-generated pushing forces separate centrosomes during bipolar spindle assembly. J.Cell Biol., 184: 365-372.

Roberts, A.P., Abaitua, F., O'Hare, P., and McNab, D., Rixon, F.J. and Pasdeloup, D. (2009) Differing roles of inner tegument proteins pUL36 and pUL37 during entry of herpes simplex virus type 1 (HSV-1). J. Virol., 83: 105-116.

2008

Chi, P., Kwon, Y., Moses, D.N., Seong, C., Sehorn, M.G., Singh, A.K., Tsubouchi, U., Greene, E.C., Klein, H.L. and Sung, P. (2008) Functional interactions of meiotic recombination factors Rdh54 and Dmc1. DNA Repair (Amst). Advance online Nov.21.

Fry, A.M. and Yamano, H. (2008) Under arrest in mitosis: Cdc20 dies twice. Nat. Cell Biol., 10: 1385-1387.

Kimata, Y., Baxter, J.E., Fry, A.M. and Yamano, H. (2008) A role for the Fizzy/Cdc20 family of proteins in activation of the APC/C distinct from substrate recruitment. Mol. Cell., 32: 576-583.

DesGeorges, A., Katsuki, M., Drummond, D.R., Osei, K., Cross, R.A. and Amos, L.A.(2008) Ma13, the S. pombe homologue of EB1, changes the microtubule lattice. Nature Struc. Mol. Biol., Advance online 14 September; doi: 10.1038/nsmb.1482.

Cross, R.A. (2008) Single molecule for the people. Nature Cell Biol., 10: 1014.

Rodriguez, M., ladowicz, E., Lanfrancone, L. and Goding, C.R. (2008) Tbx3 represses e-cadherin expression and enhances melanoma invasiveness. Cancer Res., 68: 7872-7881.

Goodall, J., Carreira, S., Denat, L., Kobi, D., Davidson, I., Nuciforo, P., Sturm, R.A., Larue, L. and Goding, C.R. (2008) Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells. Cancer Res., 68: 7788-7794.

Edymann, T., Sommariva, E., Inagawa, T., Mian, S., Klar, A.J.S. and Dalgaard, J.Z. (2008) Rtf1-mediated eukaryotic specific replication termination. Genetics, 180: 27-39.

Pontecorvi, M., Goding,C.R., Richardson W.D., and Kessaris, N. (2008) Expression of Tbx2 and Tbx3 in the developing hypothalamic-pituitary axis. Gene Expr. Patterns, 8: 411-417.

Hofemeister, H. and O'Hare, P. (2008) Nuclear pore composition and gating in herpes simplex virus-infected cells. J. Virol., 82: 8392-8399.

Kaseda, K., Crevel, I., Hirose, K. and Cross, R.A. (2008) Single-headed mode of kinesin-5. EMBO Reports, 9: 761-765.

Hoogaars, W.M.H., Barnett, P., Rodriguez, M., Clout, D.E., Moorman, A.F.M., Goding, C.R. and Christoffels, V.M. (2008) TBX3 and its splice variant TBX3 + exon 2a are functionally similar. Pigment Cell Melanoma Res., 21: 379-387.

Trickey, M., Grimaldi, M. and Yamano, H. (2008) The anaphase-promoting complex/cyclosome (APC/C) controls repair and recombination by ubiquitylating Rhp54 in fission yeast. Mol. Cell. Biol., 28: 3905-3916.

Abaitua, F. and O'Hare, P. (2008) Identification of a highly conserved, functional nuclear localization signal within the N-terminal region of Herpes Simplex Virus Type 1 VP1-2 tegument protein. J. Virol., 82: 5234-5244.

Dunn, S., Morrison, E., Liverpool, T., Molina-Paris, C., Cross, R.A., Alonso, M.C. and Peckham, M. (2008) Differential trafficking of kinesin-1 (Kif5c) on tyrosinated and detyrosinated microtubules in live cells. J. Cell Sci., 121:: 1085-1095.

Busygina, V., Sehorn, M.G., Shi, I.Y., Tsubouchi, H., Roeder, G.S. and Sung, P. (2008) Hed1 regulates Rad51-mediated recombination via a novel mechanism. Genes & Dev., 22: 786-795.

Kimata, Y., Trickey, M., Izawa, D., Gannon, J., Yamamoto, M. and Yamano, H. (2008) A mutual inhibition between APC/C and its substrate Mes1 required for meiotic progression in fission yeast. Dev. Cell, 14:: 446-454.

Theisen, U., Straube, A. and Steinberg, G. (2008) Dynamic rearrangement of nucleoporins during fungal "open" mitosis. Mol. Biol. Cell, 19: 1230-1240.

Davis, E.,Teng, H., Bilican, B., Parker, Liu, B.,Carriera, S., Goding, C.R. and Prince, S. (2008) Ectopic Tbx3 expression results in polyploidy and cisplatin resistance. Oncogene, 27(7): 976-984.

Abrahams, A. Shaheen Mowla, S., Parker, I.M., Goding, C.R. and Prince, S.(2008) UV-mediated regulation of the anti-senescence factor Tbx2. J. Biol. Chem., 283: 2223-2230.

2007

McClelland, S.E., Borusu, S., Amaro, A.C., Winter, J.R., Belwal, M., McAinsh, A.D. and Meraldi, P. (2007) The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity.  EMBO J., 26: 5033-5047.

Delmas, V., Beerman, F., Martinozzi, S., Carreira, S., Ackermann, A., Kumasaka, M., Denat, L., Goodall, J., Luciani, F. Viros, A. Demirkan, N. Bastian, B.C., Goding, C.R. and Larue, L. (2007) b-catenin induces immortalization of melanocytes by suppressing p16^INK4a expression and cooperates with N-Ras in melanoma development. Genes and Dev., 21: 33-338.

Bailey, D., Barreca, C. and O’Hare, P. (2007) Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stress-regulated intramembrane proteolysis. Traffic, 8: 1796-1814.

Hamard, P.-J., Boyer-Guittaut, M., Camuzeaux, B., Dujardin, D., Hauss, C., Oelgeschläger, T., Vigneron, M., Kedinger, C., Chatton, B. (2007) Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activity. Nucleic Acids Res., 35: 1134-1144.

Bailey, D. and O'Hare, P. (2007) Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response. Antioxidants & Redox Signaling, 9: 2305-2321.

Porter, I.M., McCelland, S.E., Khoudoli, G.A., Hunter, C.J., Andersen, J.S., McAinsh, A.D., Blow, J. and Swedlow, J.R. (2007) Bod1, a novel kinetochore protein required for chromosome biorientation. J. Cell Biol., 179: 187-197.

Goding, C.R.  (2007)  Melanoma senescence: HDAC1 in focus.  Pigment Cell Res., 20: 336-338.

Demay, F., Bilican, B., Rodriguez, M., Carreira, S., Pontecorvi, M., Ling, Y. and Goding, C.R.  (2007)  T-box factors: targetting to chromatin and interaction with the histone H3 N-terminal tail.  Pigment Cell Res., 20: 279-287.

Yamada-Inagawa, T., Klar, A.J.S. and Dalgaard, J.Z.  (2007) Schizosaccharomyces pombe switches mating type by the synthesis-dependent strand-annealing mechanism. Genetics, 177: 255-265.

Malecová, B., Gross, P., Boyer-Guittaut, M., Yavuz, S. and Oelgeschläger, T. (2007)
The Initiator Core Promoter Element Antagonizes Repression of TATA-directed Transcription by Negative Cofactor NC2. J. Biol. Chem. 282: 24767-24776.

Straube, A. and Merdes, A.  (2007) EB3 regulates microtubule dynamics at the cell cortex and is required for myoblast elongation and fusion. Current Biol., 17: 1318-1325.

Przewloka, M.R., Zhang, W., Costal, P. Archambault, V., D'Avino, P.P., Lilley, K.S., Laue, E.D., McAinsh, A.D. and Glover, D.M. (2007)  Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster.  PLoS ONE, 5:e478.

Alonso, M.C., Drummond, D.R., Kain, S., Hoeng, J., Amos, L.A. and Cross, R.A.  (2007)  An ATP-gate controls tubulin binding by the tethered head of kinesin-1.  Science, 316: 120-123.

Grant, B., McCammon, A., Caves, L.S. and Cross, R.A.  (2007)  Multivariate analysis of conserved sequence-structure relationships in kinesins: coupling of the active site and a tubulin-binding subdomain.  J. Mol. Biol., 368: 1231-1248.

Morris, J.B., Hofemeister, H. and O’Hare, P.  (2007)  Herpes simplex virus infection induces phosphorylation and delocalization of emerin, a key inner nuclear membrane protein.  J. Virol., 81: 4429-4437.

Donnelly, M., Verhagen, J. and Elliott, G.  (2007)  RNA binding by the herpes simplex virus type 1 nucleocytoplasmic shuttling protein UL47 is mediated by an N-terminal arginine-rich domain that also functions as its nuclear localization signal.  J. Virol., 81: 2283-2296.

Wu, Q., Guo, Y., Yamada, A., Perry, J.A., Wang, M.Z., Araki, M., Freel, C.D., Tung, J.J., Tang, W., Margolis, S.S., Jackson, P.K., Yamano, H., Asano, M. and Kornbluth, S.  (2007) A role for Cdc2 and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.  Curr. Biol., 17: 213-224.

Goding, C.R.  (2007)  Melanocytes-The New Black.  Int. J. Biochem. Cell Biol., 39: 275-279.

2006

Schepsky, A., Bruser, K., Gunnarsson, G.J., Goodall, J., Hallsson, J.H., Goding, C.R., Steingrimsson, E. and Hecht, A.  (2006)  The microphthalmia-associated transcription factor Mitf interacts with b-catenin to determine target gene expression Mol. Cell. Biol., 26: 8914-8927.

Carreira, S., Goodall, J., Denat, L., Rodriguez, M., Nuciforo, P., Hoek, K.S., Testori, A., Larue, L., Goding, C.R.  (2006)  Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes & Dev., 20: 3426-3439.

Verhagen, J., Donnelly, M. and Elliott, G.  (2006)
Characterisation of a novel transferable CRM-1 independent nuclear export signal in a herpesvirus tegument protein that shuttles between the nucleus and the cytoplasm.
J. Virol., 80: 10021-10035.

Moores, C.A. Perderiset, M., Kappeler, C., Kain, S., Drummond, D., Perkins, S.J., Chelly, J., Cross, R.A., Houdusse, A. and Francis, F.  (2006) 
Distinct roles of doublecortin in modulating the microtubule cytoskeleton. 
EMBO J., 25: 4448-4457. 

Barreca, C. and O’Hare, P.  (2006) 
Characterisation of a potent refractory state and persistence of herpes simplex virus 1 in cell culture.  
J. Virol., 80: 9171-9180. 

McAinsh, A.D., Meraldi, P., Draviam, V.M., Toso, A. and Sorger, P.K.  (2006)
The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.
EMBO J., 25: 4033-4049.

Fry, A.M. and Yamano, H.  (2006)
APC/C-mediated degradation in early mitosis: How to avoid spindle assembly checkpoint inhibition
Cell Cycle, 5: 1487-1491.

Cross, R.A.  (2006)  Myosin’s mechanical ratchet. 
PNAS, 103: 8911-8912.

Bilican, B. and Goding, C.R.  (2006) 
Cell cycle regulation of the T-Box Factor tbx2. 
Experimental Cell Res., 312: 2358-2366.

Hayes, M.J., Kimata, Y., Wattam, S.L., Lindon, C., Mao, G. Yamano, H. and Fry, A.M.  (2006)
Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C.
Nature Cell Biol., 8: 607-614.

Howat, T.J., Barreca, C., O'Hare, P., Gog, J.R. and Grenfell, B.T.  (2006)
Modelling dynamics of the type I interferon response to in vitro viral infection.
J.R. Soc. Interface, http://dx.doi.org/10.1098/rsif.2006.0136

Meraldi, P., McAinsh, A. D., Rheinbay, E. and Sorger, P. K. (2006) 
Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins. 
Genome Biology, 7: R23.

Xella, B., Goding, C., Agricola, E., Di Maruo, E., Caserta, A.  (2006)
The ISWI and CHD1 chromatin remodelling activities influence ADH2 expression and chromatin organization
Mol. Microbiol., 59: 1531-1541.

Stirling, J. and O’Hare, P. (2006)
CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P.
Mol. Biol. Cell, 17: 413-426.

Skoufias, D.A., DeBonis, S., Saudi, Y., Lebeau, L., Crevel, I., Cross, R.A., Wade, R., Hackney, D. and Kozielski, F.  (2006) 
S-Trityl-L-cysteine is a reversible, tight-binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression. 
J. Biol. Chem., 281: 17559-17569.

Goding, C. and Meyskens, F.L. (2006)
Microphthalmic-associated transcription factor integrates melanocyte biology and melanoma progression.
Clin. Cancer Res., 12, 1069-1073. 

Carter, N.J. and Cross, R.A.  (2006) 
Kinesin's moonwalk. 
Curr. Opin. Cell Biol., 18: 61-67.

Gross, P. and Oelgeschläger, T.  (2006) 
Core promoter-selective RNA polymerase II transcription.
Biochem. Soc. Symp. 73: 225-236.

Vengrova, S. and Dalgaard, J.Z.  (2006) 
The wild-type Schizosaccharoymces pombe mat1 imprint consists of two ribonucleotides.
EMBO Reports, 7: 59-65.

Kimata, Y. and Yamano, H.  (2006) 
Structural analysis sheds light on APC/C-mediated ubiquitylation.
Dev. Cell, 10: 4-5.

Verhagen, J., Hutchinson, I. and Elliott, G.  (2006) 
Nucleocytoplasmic shuttling of bovine herpesvirus 1 UL47 protein in infected cells. 
J. Virol.  80: 1059-1063.

2005

Yajima, J. and Cross, R.A.  (2005)  A torque component in the kinesin-1 power stroke.  Nature Chemical Biology, 1: 338-341.

Bailey, D. and O’Hare, P. (2005)  Comparison of the SUMO-1 and ubiquitin conjugation pathways during the inhibition of proteasome activity with evidence of SUMO-1 recycling.  Biochem. J.  392:  271-281.

Lödige, I., Marg, A., Wiesner, B., Malecová, B., Oelgeschläger, T. and Vinkemeier, U. (2005) Nuclear export determines the cytokine sensitivity of STAT transcription factors. J. Biol. Chem., 280: 43087-43099.

Potel, C. and Elliott, G. (2005) Phosphorylation of the herpes simplex virus tegument protein VP22 has no effect on the incorporation of VP22 into the virus but is involved in optimal expression and packaging of ICP0.  J. Virol., 79: 14088-14094.

Turnell, A.S., Stewart, G.S., Grand, R.J.A., Rookes, S.M., Martin, A., Yamano, H., Elledge, S.J. and Gallimore, P.H.  (2005) The APC/C and CBP/p300 co-operate to regulate transcription and cell cycle progression.  Nature, 438: 690-695.

Mouzakitis, G., McLauchlan, J., Barecca, C., Kueltzo, L. and O’Hare, P. (2005) Characterisation of VP22 in herpes simplex virus infected cells.  J.Virol., 79: 12185-12198.

Juang, B.-T., Izeta, A., O’Hare, P. and Luisi, B.F.  (2005)  Purification and Characterization of the Caenorhabditis elegans HCF protein and domains of human HCF.  Biochemistry, 44: 10396-10405.

Crouch, D.H., Fisher, F., La Rocca, S.A., Goding, C.R. and Gillespie, D.A.F. (2005) Viral mutations enhance the Max binding properties to the vMyc b-HLH-LZ domain.  Nucleic Acids Res., 33: 5235-5242.

Hafezi, W., Bernard, E., Cook, R. and Elliott, G.  (2005)  Herpes simplex virus tegument protein VP22 contains an internal VP16-interaction domain and a C-terminal domain that are both required for VP22 assembly into the virus particle.  J. Virol., 79: 13082-13093.

Elliott, G., Hafezi, W., Whiteley, A. and Bernard, E.  (2005)  Deletion of the herpes simplex virus VP22-encoding gene (UL49) alters the expression, localisation and virion incorporation of ICP0.  J. Virol., 79: 9735-9745.

Carter, N.J. and Cross, R.A. (2005) Mechanics of the kinesin step.
Nature, 435: 308-312.

Poot, R.A., Bozhenok, L., van den Berg, D.L.C., Hawkes, N. and Varga-Weisz, P.D.  (2005)  Chromatin remodeling by WSTF-ISWI at the replication site: opening a window of opportunity for epigenetic inheritance. Cell Cycle, 4: 543-546.

Vengrova, S. and Dalgaard, J.Z. (2005) The Schizosaccharomyces pombe imprint - nick or ribonucleotide(s)?
Current Biology, 15: R326-327.

Boyer-Guittaut, M., Birsoy, K., Potel, C., Elliott, G., Jaffray, E., Desterro, J.M., Hay, R.T. and Oelgeschläger, T.  (2005) SUMO-1 modification of human TFIID complex subunits: Inhibition of TFIID promoter binding activity through SUMO-1 modification of hsTAF5.
J. Biol. Chem., 280: 9937-9945.

Torres-Rosell, J., Machín, F., Farmer, S., Jarmuz, A., Eydmann, T., Dalgaard, J.Z. and Aragón, L. (2005) SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions.
Nature Cell Biol., 7: 412-419.

Sommariva, E., Pellny, T.K., Karahan, N., Kumar, S., Huberman, J.A. and Dalgaard, J.Z.  (2005)  Schizosaccharomyces pombe Swi1, Swi3 and Hsk1 are components of a novel S-phase response pathway to alkylation damage.
Mol. Cell. Biol., 25: 2770-2784.

Izawa, D., Goto, M., Yamashita, A., Yamano, H. and Yamamoto, M. (2005)  Fission yeast Mes1p ensures the onset of meiosis II by blocking degradation of cyclin Cdc13p.
Nature, 434: 529-533.

Kumasaka, M., Sato, S., Yajima, I., Goding, C.R. and Yamamoto, H. (2005) Regulation of melanocyte and RPE development by Xenopus laevis Mift. Dev. Dynamics, 234: 523-534.

Carreira, S., Goodall, J., Aksan, I., La Rocca, S.A., Galibert, M.-D., Denat, L., Larue, L. and Goding, C.R. (2005) Mitf cooperates with Rb1 and activates p21^Cip1 expression to regulate cell cycle progression.
Nature, 433: 764-769.

Vance, K., Carreira, S., Brosch, G.. and Goding, C.R. (2005) Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas.
Cancer Res., 65: 2260-268.

Hofemeister, H. and O’Hare, P.  (2005)  Analysis of the localization and topology of nurim, a polytopic protein tightly associated with the inner nuclear membrane.
J. Biol. Chem., 280: 2512-2521.